More than 1,100 walkers are expected to gather in downtown Houston on Saturday, May 4 in support of the Arthritis Foundation and its mission to cure arthritis and help people with arthritis live a full life.

Houston's Walk to Cure Arthritis, locally sponsored by Texas Orthopedic Hospital, will be held in Jones Plaza, 600 Louisiana Street, with onsite registration at 8:00am. To sign up for Houston's Walk to Cure Arthritis or donate to the Arthritis Foundation.

The nation's leading cause of disability, arthritis impacts four million Texans including 25,000 children.

To help bring the Houston walk to its fullest potential, the Arthritis Foundation brought together local honorees, including Vasilios Mathews, MD of Texas Orthopedic Hospital, to help excite the community and fundraise. A joint replacement surgeon, Dr. Mathews had his hip replaced for arthritis and empathizes with those suffering from the daily pain of their joint disease.

"The pain of arthritis may not be visible but is incredibly real and the number one cause of disability in America," he said. "More must be done to help cure arthritis and raising money through the Walk to Cure Arthritis will help fund critical research. As Medical Honoree, I invite families, businesses and organizations to come together for the Walk to Cure Arthritis and help us reach our $223,000 fundraising goal."

In the U.S., more than 52 million adults and 300,000 children live with arthritis. Costing the U.S. economy $156 billion dollars a year, arthritis affects one in four Americans and causes more activity limitation than heart disease, cancer or diabetes.